NASHVILLE, TN — Researchers in Nashville need volunteers for the NIH-funded AHEAD Study this winter and beyond.

November is Alzheimer’s Disease Awareness Month and researchers at Vanderbilt University Medical Center are looking for volunteers to join the AHEAD Study which tests whether intervening ahead of Alzheimer’s symptoms can prevent future memory loss and dementia.

Most people have been or will be touched by Alzheimer’s disease—whether it’s family members, friends, neighbors or colleagues. African Americans are twice as likely as non-Hispanic white Americans to have Alzheimer’s disease or a related dementia. In fact, African Americans have higher risk of dementia than any other US ethnic racial group. The AHEAD Study presents a tremendous opportunity to possibly get AHEAD of the disease before it starts.

The AHEAD Study consists of two different clinical trials testing the same investigational treatment known as BAN2401 (Lecanemab). Participants are enrolled in one of the two trials based on the level of amyloid, a protein that builds up in people who can go on to have memory problems and develop Alzheimer’s disease. Discovering a treatment that targets brain changes early means doctors may be able to one day prevent memory loss.

In addition to being Alzheimer’s Disease Awareness Month, November is also National Family Caregivers Month. Vanderbilt researchers encourage people with a family history of Alzheimer’s to learn more about the AHEAD Study and see if they are eligible to participate. According to the National Alliance for Caregiving, there are 53 million family caregivers in the United States, of which 15.7 million (26%) are caring for someone with Alzheimer’s disease or dementia. The study has a priority to enroll people who reflect the diversity of the United States and people at the greatest risk for developing Alzheimer’s disease.

The AHEAD Study seeks 1,165 participants from North America. There are more than 100 study locations worldwide, including in North America, Japan, Singapore, Australia, and Europe.

For more information or to see if you or a family member may be eligible, call Blake Wilson, 615-936-4997 or blake.wilson@vumc.org