Close Menu
    Facebook X (Twitter) Instagram
    • Home
    • About Us
    • Digital Subscription
    • Advertisement
    • Contact Us
    Facebook X (Twitter) Instagram
    The Tennessee TribuneThe Tennessee Tribune
    Advertise With Us
    • Home
      • COVID-19 Resource Center
        • Dr. Henry Louis Gates’ PSA Radio
      • Featured
    • News
      • State
      • Local
      • National/International News
      • Global
      • Business
        • Commentary
        • Finance
        • Local Business
      • Investigative Stories
        • Affordable Housing
        • DCS Investigation
        • Gentrification
    • Editorial
      • National Politics
      • Local News
      • Local Editorial
      • Political Editorial
      • Editorial Cartoons
      • Cycle of Shame
    • Community
      • History
      • Tennessee
        • Chattanooga
        • Clarksville
        • Knoxville
        • Memphis
      • Public Notices
      • Women
        • Let’s Talk with Ms. June
    • Education
      • College
        • American Baptist College
        • Belmont University
        • Fisk
        • HBCU
        • Meharry
        • MTSU
        • University of Tennessee
        • TSU
        • Vanderbilt
      • Elementary
      • High School
    • Lifestyle
      • Art
      • Auto
      • Tribune Travel
      • Entertainment
        • 5 Questions With
        • Books
        • Events
        • Film Review
        • Local Entertainment
      • Family
      • Food
        • Drinks
      • Health & Wellness
      • Home & Garden
      • Featured Books
    • Religion
      • National Religion
      • Local Religion
      • Obituaries
        • National Obituaries
        • Local Obituaries
      • Faith Commentary
    • Sports
      • MLB
        • Sounds
      • NBA
      • NCAA
      • NFL
        • Predators
        • Titans
      • NHL
      • Other Sports
      • Golf
      • Professional Sports
      • Sports Commentary
      • Metro Sports
    • Media
      • Video
      • Photo Galleries
      • Take 10
      • Trending With The Tribune
    • Classified
    • Obituaries
      • Local Obituaries
      • National Obituaries
    The Tennessee TribuneThe Tennessee Tribune
    Memphis

    UTHSC’s Miranda Receives Grant for Pediatric Bone Cancer Research

    Article submittedBy Article submittedAugust 2, 2018No Comments2 Mins Read
    Facebook Twitter LinkedIn Telegram Pinterest Tumblr Reddit Email
    Susan Miranda, Ph.D.
    Share
    Facebook Twitter LinkedIn Pinterest Email

    MEMPHIS, TN — Susan Miranda, PhD, associate professor in the Department of Orthopaedic Surgery in the College of Medicine at the University of Tennessee Health Science Center (UTHSC), has received a one-year $99,918 grant from the St. Baldrick’s Foundation to continue her research into ways to prevent the growth of osteosarcoma cells by targeting estrogen signaling.

    The St. Baldrick’s Foundation is the largest private funder of childhood cancer research grants. This year, the foundation awarded 76 grants totaling more than $19.1 million to support physician-scientists studying innovative treatment options in pediatric cancer. Among other schools awarded grants are Baylor College of Medicine, MD Anderson Cancer Center, Brigham and Women’s Hospital, and St. Jude Children’s Research Hospital.

    Dr. Miranda’s grant comes with generous support from the Sweet Caroline Fund, a St. Baldrick’s Hero Fund started to honor the memory of Caroline Richards, who was diagnosed in 2014 with osteosarcoma (a rare cancer that begins in the bones) in her right arm when she was 11 years old. She passed away a year after her diagnosis.

    Over the last three decades, the survival rate for osteosarcoma has not changed, because no targeted therapies are available. Surgery and cytotoxic chemotherapy are available options, but they are not always effective. For children diagnosed, the five-year survival rate is 69 percent.

    Estrogen is important for bone metabolism via a variety of mechanisms in a number of cells to maintain bone mineral density. It has been assumed that estrogen does not play a role in osteosarcoma, because the tumor cells are estrogen-receptor negative.

    “Normal bone cells respond to estrogen signaling and the goal of our work is to reactivate estrogen signaling to prevent osteosarcoma tumors from developing,” Dr. Miranda said. “Our long-term goal is to treat osteosarcoma patients with drugs to allow hormone therapy to be effective. These drugs are FDA-approved for other cancers and can be more rapidly applied to osteosarcoma.”

    The St. Baldrick’s Foundation is a volunteer- and donor-powered charity committed to supporting the most promising research to find cures for childhood cancers.

    Share. Facebook Twitter Pinterest LinkedIn Tumblr Email
    Article submitted

    Related Posts

    Cohen’s District Director was “an Extremely Talented Administrator”

    June 23, 2025

    Young WallStreet Traders Expands Summer Bootcamp Program to Empower Students While Bringing Financial Literacy and Empowerment Tools to Youth Across Shelby County and Beyond

    June 18, 2025

    Stop Work Order to Affect Legal Services for Immigrant Children in Tennessee The decision cuts off legal services to 26,000 children across the U.S.

    June 11, 2025

    Meharry Expands Into Memphis With Training Site at Mississippi Boulevard Church

    June 9, 2025

    BREAKING NEWS: Officers in Tyre Nichols Death Get a Pass in State Court

    May 14, 2025

    xAI Controversy Questions Black Leadership, Chamber Integrity

    May 8, 2025

    Comments are closed.

    Business

    Charlotte Knight Griffin Takes Office as TBA President-Elect

    June 30, 2025

    EXCLUSIVE OP-ED: President Joe Biden Commemorating Juneteenth

    June 19, 2025

    FUNdraising Good Times Report from Neighborhoods USA Conference in Jacksonville

    June 4, 2025
    1 2 3 … 384 Next
    Education
    Education

    Austin Peay’s MPH program receives $27K for childhood literacy initiative. Community LIFT Project to be implemented at Head Start centers this fall

    By Ethan SteinquestJune 30, 2025

    CLARKSVILLE, Tenn. – Austin Peay State University’s Master of Public Health program is on a…

    TSU, State, reach agreement to reallocate $96M to school

    June 26, 2025

    TSU student lands prestigious internship at Harvard Medical School

    June 25, 2025

    FAMU stakeholders file lawsuit to prevent Marva Johnson’s confirmation as the university’s 13th President

    June 21, 2025
    The Tennessee Tribune
    Facebook X (Twitter) Instagram
    • About Us
    • Digital Subscription
    • Store
    • Advertise With Us
    • Contact
    © 2025 The Tennessee Tribune - Site Designed by No Regret Media.

    Type above and press Enter to search. Press Esc to cancel.

    Our Spring Sale Has Started

    You can see how this popup was set up in our step-by-step guide: https://wppopupmaker.com/guides/auto-opening-announcement-popups/